Olfactory sulcus morphology in established bipolar affective disorder

T Takahashi; GS Malhi; Y Nakamura; M Suzuki; C Pantelis

Journal article

Olfactory sulcus morphology in established bipolar affective disorder

T Takahashi, GS Malhi, Y Nakamura, M Suzuki, C Pantelis

Psychiatry Research Neuroimaging | ELSEVIER IRELAND LTD | Published : 2014

DOI: 10.1016/j.pscychresns.2014.02.005

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Abstract

This MRI study examined the morphology of the olfactory sulcus, a potential marker of early neurodevelopment in 26 patients with bipolar I disorder and 24 matched controls. Bipolar patients had significantly shallower olfactory sulci bilaterally compared to controls, suggesting that neurodevelopmental abnormalities contribute to the neurobiology of bipolar disorder. © 2014 Elsevier Ireland Ltd.

University of Melbourne Researchers

Christos Pantelis Author

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RESEARCH FELLOWSHIP - PROF CHRISTOS PANTELIS

I have established and head the Melbourne Neuropsychiatry Centre within the University of Melbourne. My university position is a research ch..

Grants

Awarded by National Alliance for Research on Schizophrenia and Depression

Funding Acknowledgements

This research was supported in part by Grants-in-Aid for Scientific Research (C) (no. 22591275, 24591699) and Grants-in-Aid for Scientific Research (B) (no. 24390281) from the Japanese Society for the Promotion of Science, Health and Labour Sciences Research Grants (Comprehensive Research on Disability, Health and Welfare, H23-Seishin-Ippan-002 and H23-Seishin-Ippan-009), a Grant from Research Group For Schizophrenia, Japan, and a Research Grant from the JSPS Asian Core Program. Prof. Christos Pantelis was supported by a NHMRC Senior Principal Research Fellowship (ID: 628386), NARSAD Distinguished Investigator Award.